Susceptibilities of Nonhuman Primates to Chronic Wasting Disease
نویسندگان
چکیده
منابع مشابه
Susceptibilities of Nonhuman Primates to Chronic Wasting Disease
Chronic wasting disease (CWD) is a transmissible spongiform encephalopathy, or prion disease, that affects deer, elk, and moose. Human susceptibility to CWD remains unproven despite likely exposure to CWD-infected cervids. We used 2 nonhuman primate species, cynomolgus macaques and squirrel monkeys, as human models for CWD susceptibility. CWD was inoculated into these 2 species by intracerebral...
متن کاملChronic Wasting Disease Agents in Nonhuman Primates
Chronic wasting disease is a prion disease of cervids. Assessment of its zoonotic potential is critical. To evaluate primate susceptibility, we tested monkeys from 2 genera. We found that 100% of intracerebrally inoculated and 92% of orally inoculated squirrel monkeys were susceptible, but cynomolgus macaques were not, suggesting possible low risk for humans.
متن کاملChronic Wasting Disease
Chronic wasting disease (CWD) is a neurodegenerative disease, caused by a prion that affects cervids including deer, elk and moose. Until recently, CWD was an obscure illness that seemed to be found only in a small geographic area in northeastern Colorado and southeastern Wyoming. However, this disease has now been detected in wild and farmed cervids in many other U.S. states and Canada. Korea ...
متن کاملChronic Wasting Disease
Last Updated: October 8, 2008 Importance Chronic wasting disease (CWD) is a neurodegenerative disease, caused by a prion that affects cervids including deer, elk and moose. Until recently, CWD was an obscure illness that seemed to be found only in a small geographic area in northeastern Colorado and southeastern Wyoming. However, this disease has now been detected in wild and farmed cervids in ...
متن کاملChronic Wasting Disease
Chronic wasting disease (CWD) is a unique transmissible spongiform encephalopathy (TSE) of mule deer (Odocoileus hemionus), white-tailed deer (O. virginianus), and Rocky Mountain elk (Cervus elaphus nelsoni). The natural history of CWD is incompletely understood, but it differs from scrapie and bovine spongiform encephalopathy (BSE) by virtue of its occurrence in nondomestic and free-ranging sp...
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ژورنال
عنوان ژورنال: Emerging Infectious Diseases
سال: 2009
ISSN: 1080-6040,1080-6059
DOI: 10.3201/eid1509.090253